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Bacteriology

Vibrio, Campylobacter and H. pylori

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SAMPLE QUESTION

A patient develops profuse nonbloody diarrhea after drinking contaminated water. Small intestinal biopsies show little destructive invasion. In cultured epithelial cells, a toxin from the isolate modifies Gs alpha, and chloride secretion rises even after extracellular receptor stimulation ends.

Which intracellular sequence best explains the persistent secretion?