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General pathology and immunology

Immune laboratory tests: flow cytometry and serology

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SAMPLE QUESTION

A lymph-node sample contains an expanded population of small lymphocytes. Flow cytometry shows that these cells express CD19 and CD20 but not CD3. A smaller population expresses CD3 and CD8. Both populations occupy overlapping regions on a forward-scatter versus side-scatter plot.

Which interpretation of the expanded population is best supported by the available data?