Transcription, RNA processing, and splicing
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A 47-year-old man develops vomiting and profuse diarrhea 11 hours after eating mushrooms he collected while hiking. The gastrointestinal symptoms briefly improve, but three days after the meal he develops jaundice and confusion. Serum alanine aminotransferase is 4,250 U/L (reference 17–63), and the INR is 3.6 (reference 0.8–1.2).