Cell signaling through G proteins and second messengers
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A 29-year-old man develops profuse watery diarrhea while working in an area with a recent outbreak of waterborne illness. He has no fever or blood in the stool. Within several hours, he becomes lethargic, with dry mucous membranes, a pulse of 124/min, and a blood pressure of 84/50 mm Hg. Intravenous rehydration is started. Stool culture grows Vibrio cholerae.