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Biochemistry, cell biology, and genetics

Mitochondrial Poisons, Uncouplers & ROS | USMLE Step 1

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SAMPLE QUESTION

A 34-year-old agricultural worker develops painful oral lesions and vomiting after accidentally swallowing a herbicide stored in a beverage bottle. Over the next two days, his creatinine rises and he develops increasing shortness of breath with bilateral pulmonary opacities. The recovered product contains paraquat.

Which oxygen-derived species is formed directly during paraquat redox cycling, and which oxidant is then produced from it by superoxide dismutase?