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Biochemistry, cell biology, and genetics

GLUT vs SGLT Transporters | USMLE Step 1

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SAMPLE QUESTION

A 3-year-old girl is evaluated for developmental delay and seizures that are most frequent before breakfast. Her parents also describe episodes of unsteady walking before meals. A blood sample obtained after a 4-hour fast immediately before lumbar puncture shows a glucose concentration of 88 mg/dL. Cerebrospinal fluid glucose is 27 mg/dL; its cell count and protein concentration are normal.

Which additional finding would most strongly support a defect in the transporter responsible for this pattern?